DNA Testing Centre Inc. (DTC) was the first company to offer online purchases of laboratory semen detections in 2000. DTC developed an in-house laboratory procedure for a 3 part semen detection including Prostate Specific Antigen (PSA), microscopic inspection, and the Acid Phosphatase (AP) test in 2002. DTC developed and sold the first non-presumptive home semen detection test in 2003.
Semen and Sperm Detection Inc. (SSDI) was formed as a corporation dedicated to developing and performing semen detection tests in 2005. In February 2007, SSDI added the saliva detection to every standard test, at no additional charge. In August 2011, SSDI added a sperm protein (SP10) test to compliment a positive PSA test result. On 21 June 2012, SSDI became the only stand-alone ISO17025 forensically accredited serology laboratory in existence. SSDI has performed 3200+ laboratory semen detections and has sold over 50,000 PSA semen detection test kits to forensic laboratories and individual customers for home use.